The Twins scored the last four runs in the game, but they came up short in an 8-7 loss to Boston which left them with a split in their four game series with the Red Sox.
Minnesota starter Tommy Milone gave up all eight Boston runs in less than five innings of work.
A year ago, Rick Porcello was hearing nearly as many boos as cheers in Fenway Park.
Now, he’s piling up wins in front of the home fans.
Porcello became the first Boston pitcher in 55 years to open a season 10-0 in Fenway, and Hanley Ramirez and Travis Shaw both hit a three-run homer as the Red Sox beat the Minnesota Twins.
Juan Centeno, Kennys Vargas and Byron Buxton accounted for the seven Minnesota runs batted in.
The Twins are off Monday before beginning a six-game homestand Tuesday.