Mike Napoli and David Ortiz hit consecutive homers with one out in the 10th inning and the Boston Red Sox rallied past Minnesota 2-1 Wednesday, sending the Twins to their fifth straight loss.

Boston was held to one hit — a fifth-inning double by Daniel Nava — before the homers.

The Twins took a 1-0 lead in the top of the 10th on Chris Parmelee’s two-out home run off Red Sox closer Koji Uehara.

But after Dustin Pedroia flied out to begin the Boston 10th, the Red Sox connected against Casey Fien to complete a three-game sweep.

Ortiz hit his drive down the right-field line and pumped his fist toward the Boston dugout as he headed toward first base. Napoli hit his shot into the center-field bleachers.