The Chiefs placed Jamaal Charles on injured reserve Tuesday after the star running back tore the ACL in his right knee while making a cut against the Chicago Bears.
Charles had an MRI on Monday that confirmed the extent of the injury.
The Chiefs filled his roster spot by promoting running back Spencer Ware from the practice squad. Ware is a former sixth-round pick out of LSU who spent the offseason with Kansas City.
The Chiefs also released linebacker Tyrell Adams, cornerback Jeremy Harris and offensive lineman Daniel Munyer from the practice squad Tuesday.
Running back Darrin Reaves, offensive lineman Michael Liedtke, cornerback Saalim Hakim and linebacker Jayson DiManche were signed to replace them.
